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Biophysics Motor

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Open Unknowns
0
Cross-Domain Bridges
1
Active Hypotheses

Open Unknowns (1)

Unknown How does the flagellar motor dynamically regulate the number of active MotA/MotB stator units in response to proton motive force, load, and environmental conditions ΓÇâ and what is the mechanochemical mechanism of stator incorporation and release? u-flagellar-motor-stator-number-regulation-pmf

Active Hypotheses

Hypothesis Flagellar motor stator assembly is a mechanosensitive process: stators are recruited from a cytoplasmic pool in response to load (torque demand), with PMF controlling the free energy of stator-peptidoglycan binding ΓÇâ making the motor a biological torque sensor that self-optimizes stator number for current mechanical load. medium

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