Map the unknowns.

Science already lists what it knows. This lists what it does not — and lets you click one test. That is the whole product.

A landscape filling in. Each color is a habitat. Gold is the one that wraps around the edges.

Do this first · a few minutes · no account

Habitat loss and percolation are the same math

In ecology, a landscape can fall into isolated patches. In physics, a grid can lose its giant connected cluster. This project stores that claim and lets you run a check. One button.

  1. A claim that two fields share the same math.
  2. A test you can run in the browser.
  3. The picture is one landscape, not the average. The button runs four widths, 400 times each, and reports that fit.
Then look around

More open questions

A slice of what is still unknown. You do not need to add anything to look.

What is in here
1411open questions 1124claimed links 1275testable ideas 11early notes 3863graph nodes 4522graph edges

Stuck? How to use this · Why it exists

From the developer: why I am building this. If you run this site, not visiting: keep the catalog honest.

Unknown
A named open question science cannot yet answer.
Bridge
A claim that two fields share the same math.
Test
A check you can run on a bridge. We also call this Crosscheck.
Record
One catalog entry. You add one at a time.
1,124 cross-domain bridges 1,411 open unknowns • 1,275 hypotheses 3,863 linked records on the map
Local file: serve from the repo root with python -m http.server 8765 or use the hosted hub.
Add an open question

This site is for looking. To add something, you write one short record and a person reads it before it joins the catalog. Longer walkthrough: first records guide.

  1. Get a copy of the catalog

    Download the project so you can add one record on your computer. You do not need to know Git — the project page has a green Code button, then Download ZIP.

  2. Pick one thing to add

    An open question, a testable idea, or a claimed link between two fields — not all three at once.

  3. Edit that one record

    Copy a similar file and change the title, summary, and references. Records are short structured notes. The file format is a later detail.

  4. You can skip the local check

    Automated checks run when you send it. If you already operate this site, the local check is on the operator list.

  5. Send it for review

    A person reads it before it joins the catalog. On the project site that is “Open a review.”

Policy tour (optional — after you picked a door)
  1. Know what you're joining

    Vision, motivation, and why this infrastructure matters for science.

  2. Scope and quality bar

    What lives here, what doesn't, and the rigor expected of every entry.

  3. Rigor: hypotheses vs. findings

    The evidence bar, claims discipline, and output conventions. Read before proposing any scientific claims.

  4. Integrity, data, and conduct

    Ethics policy, what data may be committed, and community norms.

More tests of bridges

Start with the habitat example at the top. These are other checks of other claims. A test in the browser is enough for a first visit. How tests work

Cluster size distribution test — below p_c, does the finite cluster size distribution follow a power law with exponent…

executed last run: CONFIRMED

Protocol p-b-habitat-percolation-ecology-cluster-exponent · desktop

Run in browser → Bridge explainer

Does a smaller landscape break apart at a different point than a huge one?

executed last run: CONFIRMED

Protocol p-b-habitat-percolation-ecology-fss · desktop

Run in browser → Bridge explainer

Early-warning indicator test — does 2D Ising magnetisation near T_c show critical slowing down (rising variance and AR1…

executed last run: CONFIRMED

Protocol p-b-ising-social-dynamics-ewi · desktop

Run in browser → Bridge explainer

Finite-size epidemic threshold — does bond percolation p_c(N) on ER graphs shift as |p_c(N)-p_c(inf)| ~ N^(-1/nu_bar) w…

confirmed last run: CONFIRMED

Protocol p-b-percolation-epidemiology-fss · desktop

Open in Colab → Bridge explainer

Synthetic-lattice giant-component fraction as a percolation-derived treatment-response metric

ready last run: INCONCLUSIVE

Protocol p-b-percolation-oncology-gcc · desktop

Run repro → Bridge explainer

Orphan and missing cross-reference targets

Read-only list built from the same catalog scan as the knowledge graph (not a scientific ranking). Fixing stale IDs and missing links keeps the graph truthful for everyone. Regenerate api/v1/orphan_xref_panel.json with python scripts/export_orphan_xref_panel.py after catalog edits — see docs/DEV_DASHBOARD.md.

Broken cross-reference means a YAML file points at an ID that does not exist (typo, renamed record, or missing target). The graph cannot draw that link until the ID is fixed or the reference is removed.

Quick fix (three steps):

  1. Pick a row below and open the source file (links in the table).
  2. Correct the related_* ID in that YAML file so it matches a real catalog ID.
  3. Open a PR → wait for CI green → merge → if a graph rebuild bot PR appears, merge that too.

This table shows at most 100 rows from the export — not every xref issue in the repo.

Loading contribution targets…

High-connectivity bridges

Read-only list of existing bridges ranked by undirected catalog-graph degree (not a scientific ranking and not a CONFIRMED or INCONCLUSIVE Crosscheck outcome). Higher degree means more catalog links — leverage for a contributor looking where to connect next. Harvest rank and curator score are specified for a later phase and are not computed here. See docs/HUB_RECOMMENDATIONS.md.

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Curated cross-domain engines

Six curated thematic lenses — shortcut entry points into representative bridges in the catalog, not exhaustive domain coverage.

Maintainer playbook (regenerate stats, domain pages, breakthrough cards): docs/DEV_DASHBOARD.md.

Scientific Pioneers

Foundational scientists whose work seeds cross-domain bridges — including underappreciated contributions ripe for rediscovery.

⚡

Nikola Tesla

AC power · Wireless energy · Bladeless turbine · Earth-ionosphere resonance

🌊

James Clerk Maxwell

Unified electromagnetism · Statistical mechanics · Maxwell's demon

🔥

Ludwig Boltzmann

S = k ln W · Arrow of time · Statistical foundations

🔮

Emmy Noether

Symmetry → conservation laws · Abstract algebra · Gauge invariance

📡

Claude Shannon

Information entropy · Channel capacity · Boolean circuits

🤖

Alan Turing

Turing machine · Halting problem · Morphogenesis reaction-diffusion

⚛️

Richard Feynman

QED path integrals · Feynman diagrams · Quantum computing pioneer

🌽

Barbara McClintock

Transposable elements · Genome plasticity · Epigenetic regulation

🐢

Charles Darwin

Natural selection · Common descent · Sexual selection · Earthworm geology

🔬

Rosalind Franklin

Photo 51 · DNA X-ray crystallography · Virus structure · Carbon microstructure

🎮

John von Neumann

Stored-program computer · Game theory · Quantum formalism · Self-reproducing automata

🌌

Albert Einstein

Special & general relativity · Photoelectric effect · Brownian motion · Bose–Einstein condensate

💻

Ada Lovelace

First algorithm · General-purpose computing vision · Analytical Engine programming

Breakthrough Gaps

World-reshaping breakthroughs stalled by cross-domain knowledge gaps. Cards below are generated from the breakthrough-gaps catalog. Click a card to open that record; Alt-click (Option-click on macOS) jumps to Search with that title.

TRL 7

Economically Viable Direct Air Capture of CO2

Direct air capture (DAC) at ~$100/tonne CO₂ (from current $400–1,000/tonne) would make it economically viable to remove atmospheric CO₂ at the gigatonne scale required to meaningfully address climate change. At $100/ton…

TRL 6

Programmable mRNA Therapeutics Beyond COVID Vaccines

The COVID-19 mRNA vaccines (BioNTech/Pfizer, Moderna, 2020–2021) proved the mRNA platform at TRL 9: design-to-manufacture in months, high efficacy, large-scale production. The platform is now being extended to personali…

TRL 5

High-Bandwidth Brain-Computer Interfaces for Restoring and Augmenting Neural Function

High-bandwidth brain-computer interfaces (BCIs) — capable of reading and writing neural activity at the resolution of individual neurons across large brain areas — would enable restoration of motor function in paralysis…

TRL 4

Commercial Fusion Energy — From NIF Ignition to Grid-Scale Power

Nuclear fusion — combining hydrogen isotopes to release energy via E=mc² — offers effectively unlimited, low-carbon electricity with no long-lived nuclear waste and inherent safety (no chain reaction, self-extinguishing…

TRL 4

Liquid biopsy for universal early-stage cancer detection

Detecting any cancer type at stage I from a blood draw — using circulating tumor DNA (ctDNA), cell-free methylation signatures, exosomes, or protein biomarkers — with less than 1% false positive rate and greater than 90…

TRL 4

Low-Temperature Electrochemical Water Splitting for Green Hydrogen

Scalable, low-cost water splitting using earth-abundant catalysts operating near room temperature would make green hydrogen competitive with natural gas reformation, enabling carbon-neutral fuels, long-duration grid sto…

TRL 4

Net energy gain controlled nuclear fusion at commercial scale

In December 2022, the National Ignition Facility achieved Q_fusion > 1 for the first time — the fusion reaction released more energy than the laser energy deposited in the fuel capsule. However, accounting for wall-plug…

TRL 3

Artificial and Enhanced Photosynthesis — Closing the Efficiency Gap from 1-2% to Theoretical Maximum

Natural photosynthesis captures ~1-2% of incident solar energy as chemical energy in biomass — orders of magnitude below the theoretical maximum efficiency (~11% for oxygenic photosynthesis, limited by thermodynamics of…

TRL 3

Cross-Disciplinary Scientific Discovery — Systematic Infrastructure for Cross-Domain Mathematical Bridge Translation

Scientific literature grows at approximately 4% per year, doubling every 17 years. As of 2024, PubMed alone indexes over 37 million articles; the total corpus of peer-reviewed science across all fields exceeds 100 milli…

TRL 3

Disease-Modifying Alzheimer's Therapy — Resolving the Causal Mechanism

Alzheimer's disease (AD) affects 55 million people worldwide and is the leading cause of dementia. After 25 years and >100 failed clinical trials, the amyloid hypothesis (Hardy & Higgins 1992) received partial vindicati…

TRL 3

Fault-Tolerant Quantum Computation at Practical Scale

A fault-tolerant quantum computer with ~1,000 error-corrected logical qubits would break RSA-2048 encryption, simulate quantum chemistry at pharmaceutical-design accuracy (protein folding, drug binding), and solve optim…

TRL 3

Fault-tolerant scalable quantum computing with more than one million logical qubits

Current quantum computers have 1,000-10,000 physical qubits but physical error rates of 0.1-1% per gate, far above the threshold needed for useful computation. Quantum error correction using surface codes requires appro…

TRL 3

Mechanistic understanding and reversal of biological aging

Aging is the largest single risk factor for cancer, heart disease, neurodegeneration, and metabolic disease, yet its mechanism is debated. The leading candidate theories include: epigenetic entropy (information theory o…

TRL 3

New Antibiotic Classes and Alternative Strategies to Overcome Antimicrobial Resistance

Antimicrobial resistance (AMR) is projected to cause 10 million deaths per year by 2050 (O'Neill Review 2016), exceeding cancer mortality. The WHO classifies AMR as one of the top 10 global public health threats. The la…

TRL 3

Rational de novo protein design for arbitrary function

AlphaFold2 and ESMFold solve the forward problem — predicting 3D structure from amino acid sequence — with near-experimental accuracy. The inverse problem remains largely unsolved: designing a novel sequence that will f…

TRL 2

Ambient-Pressure Room-Temperature Superconductivity

A material that superconducts at room temperature and ambient pressure would eliminate resistive losses in electrical grids (~5–10% of generated power), enable compact MRI and fusion magnets without cryogenic infrastruc…

TRL 2

Identifying the neural correlates of consciousness and subjective experience

The hard problem of consciousness — why and how physical processes in the brain give rise to subjective experience (qualia) — has no agreed scientific framework. The easy problems (explaining cognitive functions like at…

TRL 2

Whole-brain single-neuron resolution recording in awake behaving mammals

No technology can simultaneously record all ~86 billion neurons in a human brain at single-neuron resolution during natural behavior. Current state-of-the-art (Neuropixels probes) records roughly 10,000 neurons simultan…

TRL 3

Kilometer-scale global climate model for decadal regional prediction

Current operational global climate models run at 25-100 km horizontal resolution. At this resolution, key processes governing regional climate — mesoscale convective systems, cumulus convection, cloud microphysics, orog…

TRL 3

Neuromorphic computing at scale — brain-matched energy efficiency for AI inference

The human brain performs general-purpose intelligence at approximately 20 watts. Running a 70-billion parameter large language model requires ~70 watts per token generated at the GPU level, and a full inference data cen…

TRL 3

Post-Treatment Lyme Disease Syndrome (PTLDS) — Mechanism and Cure

Borrelia burgdorferi, the Lyme disease spirochete, causes persistent debilitating symptoms in 10–20% of patients even after standard antibiotic treatment. PTLDS (sometimes called chronic Lyme disease) involves fatigue,…

TRL 3

Rational engineering of soil microbiomes for carbon sequestration and crop yield

Soil contains approximately 10^9 microorganisms per gram, representing more than 10,000 species per sample interacting through metabolic exchange, competition, and mutualism in networks too complex to model from first p…

TRL 2

Programmable matter — reconfigurable materials that change shape and function on demand

Materials that can autonomously reconfigure their macroscopic shape, stiffness, and function in response to external commands do not exist beyond proof-of-concept demonstrations at millimeter scale. Shape memory alloys…

TRL 2

Scalable removal and degradation of ocean microplastics

Approximately 170 trillion plastic particles are estimated to be in the ocean, with an additional 8-10 million tons entering annually. Macro-plastic removal by systems such as The Ocean Cleanup is technically feasible b…

Automated knowledge-graph analysis

Three scripts that continuously mine the knowledge graph — surfacing gaps, proposing novel cross-domain connections, and flagging low-quality entries for human review.

Loading AI proposal counts…
🔭

Bridge Proposals

Domain pairs with high unknown density and no existing bridge — the most fertile candidates for the next cross-domain discovery.

View proposals ↗
🎯

Priority Targets

Unknowns with no hypothesis or bridge edge — the highest-impact contribution opportunities in the graph today.

View targets ↗
✅

Quality Audit

Automated quality checks across all 401 catalog entries — errors, warnings, and improvement opportunities surfaced automatically.

View audit ↗
🧪

Hypothesis Generator

Pattern-matching engine that detects which mathematical framework (phase transitions, information theory, scaling laws) best connects two domains, then drafts bridge YAMLs for expert review.

How it works →
📚

Citation Index

Papers cited across multiple bridges — the most cross-domain influential works in the scientific literature. Shannon, Turing, Fisher, and their equivalents.

View index →

Static JSON endpoints

No authentication. No rate limits. Served directly from GitHub Pages. Base URL: https://kr8zysho3.github.io/Universal-Science-Discovery/api/v1/

How fields connect

Pick two fields. The map shows a real path through this catalog — not a guess.

Ask how two fields connect. The map answers with a shortest path through real catalog records.

3863 records  ·  4522 connections
Loading the map…
Claimed link
Open question
Testable idea
Early note
Connections
answers a question
suggests a testable idea
related claim
shared math

Pick a workstream, own it

Development is divided into independent areas. Find one that fits your skills, comment on an open issue to claim it, and open a draft PR early. Full details: WORKSTREAMS.md.

Step 1 — Claim
Find an issue labeled status:needs-owner. Comment "I'm taking this." A maintainer assigns it to you.
Step 2 — Branch
Create feat/<area>/<slug> from main. Open a draft PR immediately to signal what you are working on.
Step 3 — Ship
All CI must pass. Mark ready for review. One maintainer approval required. main is branch-protected — no direct pushes.
Content
⚛️ Physics
Add unknowns and hypotheses in quantum, particle physics, cosmology.
type:contentarea:physics
Browse issues ↗
Content
🧬 Biology
Seed unknowns in aging, oncology, ecology, and molecular biology.
type:contentarea:biology
Browse issues ↗
Content
💻 Computer Science
First CS unknowns needed. AI/ML, algorithms, and discovery systems.
type:contentdifficulty:starter
Browse issues ↗
Content
🌐 New Discipline
Propose Chemistry, Neuroscience, Climate Science, or another domain. Needs 3 seed entries and maintainer sign-off.
area:new-disciplinedifficulty:intermediate
Propose ↗
Engineering
📡 Ingest Pipeline
Extend the arXiv OAI-PMH harvester. Add OpenAlex, PubMed, or Semantic Scholar sources. Python + pytest.
type:toolingarea:ingest
Browse issues ↗
Engineering
📐 Schema & Validation
Improve YAML schemas, add new entry types (method, dataset), tighten CI validation rules.
type:toolingarea:schema
Browse issues ↗
Engineering
🕸️ Knowledge Graph
Build graph layer from YAML entries. RDF/JSON-LD export, NetworkX or Neo4j. Coordinate before starting.
area:knowledge-graphdifficulty:advanced
Browse issues ↗
Engineering
⚙️ Infrastructure & CI
GitHub Actions workflows, dependabot, link checking, CI reliability. YAML + shell.
type:toolingarea:infrastructure
Browse issues ↗
Docs & Design
📚 Documentation
Improve policy docs, onboarding guides, methodology. Good first workstream for non-coders.
type:docsdifficulty:starter
Browse issues ↗
Docs & Design
🖥️ Dashboard & Site
This hub and the MkDocs site. Vanilla HTML/CSS/JS and Markdown. Ship hub changes with the PR that motivated them.
area:dashboardtype:tooling
Browse issues ↗
Issue label key
difficulty:starter difficulty:intermediate difficulty:advanced status:needs-owner status:in-progress type:content type:tooling type:docs type:bug
Start with difficulty:starter + status:needs-owner. Full label guide in WORKSTREAMS.md.

University-ready robustness (v1.3)

Foundation and v1.1 Core Development are shipped. Public launch (outreach, DNS, arXiv submit) is parked. Below is the current engineering slice — see ROADMAP.md.

Milestone progress

Active
Phase 0 Foundation complete — governance, schemas, CI, catalog seed, graph, hub.
v1.1 Core Development shipped (PR #308) — 4/4 seed Crosscheck CONFIRMED, generate/promote path, hub recommendations.

0 / 4 v1.3 items complete

Ring = completed v1.3 items only. Parked launch work is not on this list.

    Recent commits

    All commits ↗
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    CI Pipelines

    Actions ↗
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    Where to add knowledge

    This hub does not edit the catalog — it links to the folders and guides where you add YAML in your clone. Start with HAPPY_PATH_FIRST_RECORDS.md for your first unknown + hypothesis PR.

    ⚛️
    Physics
    u-dark-matter-microphysics
    1
    Unknowns
    1
    Hypotheses
    🧬
    Biology
    u-aging-interventions-translatability
    1
    Unknowns
    1
    Hypotheses
    💻
    Computer Science
    cross-domain discovery algorithms
    0
    Unknowns
    0
    Hypotheses

    Stream A — first records

    Step-by-step: validate setup → add u-… unknown → add h-… hypothesis → open PR.

    Unknowns catalog

    Research gaps tracked as u-… YAML files under unknowns-catalog/.

    Hypotheses

    Testable proposals as h-… YAML with evidence links and falsification criteria.

    Cross-domain bridges

    Explicit connections between fields studying the same phenomenon — the anti-tunnel-vision layer. Schema: b-… YAML.

    Schemas & templates

    YAML schemas for validation and PR/issue templates for structured contributions.

    Contribution guide

    Rules of the road, AI use policy, and ingest integration notes.

    AI assistants (Cursor)

    If you use Cursor or other agents — rules and agent-specific policy.

    Understand the architecture

    Vision, roadmap, system architecture, and outreach framing.

    Repo entry & narrative

    Default landing for new visitors; overview of all major areas.

    Roadmap & phases

    North-star vision through 2035, phase milestones, and guiding principles.

    System architecture

    Discovery Core, Human Layer, AI Layer, and the Integration & Data Layer.

    Outreach framing

    Accurate language for external conversations and contributor recruiting.

    Trust, licensing, and how we run it

    Governance, legal framework, conduct, and the quality bar that makes contributions credible.

    Legal & licensing

    What the repo may host; third-party attribution and IP policy.

    Governance & ethics

    Decision-making structure, ethics framework, and integrity requirements.

    Quality bar

    CI gates, review lanes, definition of done — the anti-sloppiness playbook.

    Collaboration & reviews

    Review expectations, issue labels, and working group norms.

    Cadence & operations

    Branch protection, CI gates, and the daily operating rhythm.

    Maps & traceability

    From "this file" to "what policy it enforces" — audit trails and the full onboarding path.

    Doc map

    Guiding document → behaviours it governs.

    Repository manifest

    Full path index with governing policy per file — used for audits.

    Full onboarding path

    ~30-minute walkthrough covering every major document.

    Data & ingestion (technical)

    Phase A/B metadata plans, ingest envelope schema, and example data.

    Live checklist & roadmap

    Doc discipline: at each milestone or feature merge, update README, CHANGELOG (Unreleased), relevant docs/, and this hub if links change. · Pull requests · Open issues · CHANGELOG.md

    .planning/STATE.md

    Workspace state
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    ROADMAP.md

    Phase 0–4 → 2035
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